Diseases Which Can Be Treated

Stem cells have great potential for curing diseases, alleviating sufferings and saving lives. With every clinical study and breakthrough, the vision of stem cell treatment becomes definite.

ICMR Approved Hematopoetic Stem Cell Transplantation (HSCT) theropies
Adults (generally ≥ 18 years of age)
  • Acute Myeloid Leukemia (AML)
  • Acute Promyelocyte Leukemia (APML)
  • Acute Lymphoblastic Leukemia (ALL)
  • Chronic Myeloid Leukemia (CLL)
  • Myelodysplastic Syndromes (MDS)
  • Therapy related AML/MDS
  • Myelofibrosis & Myeloproliferative diseases
  • Plasma Cell Disorders
    • Myeloma
    • Plasma Cell Leukemia
    • Relapse after autologous transplant
  • Hodgkin Lymphoma (HL)
  • Diffuse Large B-cell Lymphoma
  • Follicular Lymphoma
  • Mantle Cell Lymphoma
  • T-cell Lymphomas
  • Lymphoplasmacytic Lymphomas
    • Primary refractory, sensitive
    • Primary refractory, resistant
    • First or greater relapse, sensitive
    • First or greater relapse, resistant
    • Relapse after autologous transplant
  • Burkitt’s Lymphoma
  • Cutaneous T-cell Lymphoma
  • Plasmablastic Lymphoma
  • Chronic Lymphocytic Leukemia (CLL)
  • Solid tumors
    • Germ cell tumor, relapse
    • Germ cell tumor, refractory
    • Ewing’s sarcoma, high risk
  • Non – Malignant diseases
    • Severe Aplastic Anemia, new diagnosis
    • Severe Aplastic Anemia, relapse/refractory
    • Fanconi’sAnemia (FA)
    • Dyskeratosis Congenita
    • Sickle Cell Disease (SCD)
    • Hemophagocytic Syndromes, refractory
    • Mast Cell Diseases
    • Common Variable Immunodeficiency(CVID)
    • Wiskott-Aldrich Syndrome (WAS)
    • Chronic Granulomatous Disease (CGD)
Pediatric (generally < 18 years of age)
  • Acute Myeloid Leukemia (AML)
  • Acute Lymphoblastic Leukemia (ALL)
  • Chronic Myeloid Leukemia (CML)
  • Myelodysplastic Syndromes (MDS)
  • T-cell Non-Hodgkins’ Lymphoma (T-NHL)
  • Lymphoblastic B-cell Non-Hodgkins’ Lymphoma (non-Burkitt)
  • Burkitt’s Lymphoma
  • Hodgkins’Lymphoma
  • Anaplastic Large Cell Lymphoma
  • Solid tumors
    • Germ cell tumor, relapse
    • Germ cell tumor, refractory
    • Ewing’s sarcoma, high risk or relapse
    • Neuroblastoma, high risk or relapse
    • Wilm’s tumor, relapse
    • Osteosarcoma, high risk
    • Medulloblastoma, high risk
    • Other malignant brain tumors
  • Non – Malignant diseases
    • Severe Aplastic Anemia, new diagnosis
    • Severe Aplastic Anemia, relapse/refractory
    • Fanconi’s Anemia (FA)
    • Dyskeratosis Congenita
    • Blackfan-Diamond Anemia
    • Sickle Cell Disease (SCD)
    • Thalassemia Major
    • Congenital Amegakaryocytic Thrombocytopenia
    • Severe Combined Immunodeficiency (SCID)
    • T Cell Immunodeficiency, SCID variants
    • Wiskott-Aldrich Syndrome (WAS)
    • Hemophagocytic Disorders
    • Lymphoproliferative Disorders
    • Severe Congenital Neutropenia
    • Chronic Granulomatous Disease (CGD)
    • Other Phagocytic Cell Disorders
    • Immune Dysregulation Polyendocrinopathy Enteropathy, X – linked (IPEX) Syndrome
    • Juvenile Rheumatoid Arthritis (JRA)
    • Systemic Sclerosis (SS)
    • Other Autoimmune and Immune Dysregulation Disorders
    • Mucopolysaccharoidoses (MPS-I and MPS-VI)
    • Other Metabolic Diseases
    • Osteopetrosis
    • Globoid Cell Leukodystrophy (Krabbe)
    • Metachromatic Leukodystrophy
    • Cerebral X-linked Adrenoleukodystrophy
Reference

Source: Majhail NS, Farnia SH, Carpenter PA, Champlin RE, Crawford S, Marks DI, Omel JL, Orchard PJ, Palmer J, Saber W, Savani BN, Veys PA, Bredeson CN, Giralt SA, LeMaistre CF; American Society for Blood and Marrow Transplantation. Indications for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation. Biol Blood Marrow Transplant. 2015 Nov;21(11):1863-9